Welcome to Epock’s home page!

Epock is a program specialized in rapid pocket volume evaluation for molecular dynamics simulations. This open-source package includes the C++ source code of the command-line program version, Python scripts to easily plot the program output, and a graphical user interface plugin for VMD.


  • 2018-07-05: Epock 1.0.5 is available
  • 2017-10-12: Epock 1.0.4 is available
  • 2015-12-07: Epock 1.0.3 is available
  • 2014-12-12: Epock’s paper accepted to Bioinformatics
  • 2014-01-21: Website is online!
  • 2014-01-21: Epock first release candidate available!

How to cite Epock

Here is a full citation for Epock:

Epock: rapid analysis of protein pocket dynamics

Benoist Laurent, Matthieu Chavent, Tristan Cragnolini, Anna Caroline E. Dahl, Samuela Pasquali, Philippe Derreumaux, Mark S.P. Sansom, Marc Baaden

Bioinformatics 2014

doi: 10.1093/bioinformatics/btu822


Binaries and source code are available in the download section. The installation intructions are available in Epock’s installation guide.

Contact and support

For any general purpose question on Epock, please contact benoist.laurent [at] gmail.com To report any bug or suggest enhancements, please use Epock’s issue tracker